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Mehandru and Merad reviewed the many clinical manifestations of long-haul COVID, including systemic and musculoskeletal manifestations (chronic fatigue and fibromyalgia symptoms), psychiatric symptoms (insomnia, depression, anxiety, neurocognitive deficits), autonomic and cardiovascular, GIS and renal and respiratory manifestations [71]

That fits cleanly into the 28-day post-reconstitution shelf life if you increase dosing frequency or dose amount

The prevention of intestinal barrier dysfunction by secretory IgA, along with its immunomodulatory properties, may play a role in IBD, including ulcerative colitis and Crohns disease (183)

The clinical features of Se toxicity mainly include brittle hair and nail loss, gastrointestinal disorders, rash, rickets and neurological disorders (116)