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Longer follow-up will be required because all but 47 patients were alive at the time of analysis, and there was a crossover to the study drug on progression from placebo, making analysis of OS problematic

Common distant sites (beyond the skin and regional subcutaneous tissue) are as follows: Lungs Liver (and other gastrointestinal organs, less commonly) Bone Central nervous system (brain, meninges, etc...) Melanoma Staging (TNM) Primary Tumor (T) Thickness