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The intracellular concentrations of vitamin B12 can be inferred through the total plasma concentration of homocysteine, which can be converted to methionine through an enzymatic reaction that uses 5-methyltetrahydrofolate as the methyl donor group

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High BPA-induced increases in GAD levels/GABA synthesis would decrease bipolar cell responses, which was observed in both patch clamp and ERG recordings from this treatment group (72 hpf exposed adults)