As GLP-1 medications work on the brain and body to reduce appetite and promote weight loss, and cannabis can also affect appetite and metabolism, it is important to understand the potential implications of combining these substances
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Clinical and experimental studies suggest that C-peptide replacement therapy may: Improve renal blood flow and filtration balance
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In clinical trials of once-daily or BID GLP-1 receptor agonists (liraglutide, lixisenatide, or exenatide BID), mean changes in body weight were 2.1 to 2.9 kg for monotherapy and +0.3 to 3.6 kg in combination with oral antihyperglycemic therapies (13,14,18)