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25 These measures reflect growing concern over the sustainability of widespread GLP1 use, especially as off-label demand continues to rise

Comparative Trials Head-to-head data suggest tirzepatide (Zepbound) achieved ~20.2% mean weight loss at 72 weeks versus ~13.7% with semaglutide (Wegovy)

Addressing systemic inflammation through dietary changes, sleep optimization, and stress management creates a more favorable environment for peptide-mediated brain repair

Nausea was the most common side effect reported, she said

Drug-related, post-inflammatory or systemic pigmentation , usually diffuse rather than a single small macule