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The presence of HO-1 significantly reduces the levels of inflammatory markers associated with diabetic wounds such as TNF-, IL-1, IL-6, iNOS, COX2, MCP-11, and MIP-1, while simultaneously boosting the levels of IL-10 [126]

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These data revealed that Cagri generally had a similar binding mode to amylin peptides but distinct receptor complex dynamics at the calcitonin-family receptors compared to other peptides

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