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Researchers enrolled 11 normal men in a randomized, double-blinded cross-over study

Further, qPCR analysis revealed upregulation of three detoxification enzymes, cytochrome P450, glutathione S-transferase, and carboxylesterase in ToCV-infected insects compared to non-infected insects 16

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Most evidence seems to suggest that not everyone can smell the odor, though some scientists think that not everyone produces it