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Collectively, the nervous, endocrine, and immune systems form a multidimensional cross-regulatory network through the BGA, and its dysfunction represents a key mechanism in the development of GERD

The effects of metformin are compatible with previous results from animal studies with metformin and other biguanide drugs [62]

Oral supplements must pass through the digestive system before the body can absorb and use them

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It's a challenge because of the need for frequent administration, but an opportunity because it allows for precise control over exposure, enabling researchers to fine-tune study parameters with greater accuracy