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The primary endpoint, MACE, was the time to first occurrence of a three-part composite outcome which included cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke

The chronic unpredictable stress model was also associated with similar neurobehavioural changes[55]

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With a molecular weight of 45 kDa, holoTC is readily filtered through the renal glomeruli, and then re-internalized by multiple receptor-dependent endocytic processes (via the megalin/cubilin/amnionless receptor complex) (57, 58)