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Psychiatry 68 , 675690 (2011)

They will also set an upper limit on the total weekly dose (for example, some experts recommend not exceeding approximately 300 mg per week in subcutaneous dosing without further evaluation) to minimize any risk of adverse effects

p = 0.020

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If gastrointestinal symptoms like upset stomach are disrupting your sleep, talk to your healthcare provider about dose adjustments or symptom management