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Morabito C, Rovetta F, Bizzarri M, Mazzoleni G, Fan G, Mariggi MA

If the lyophilised powder experienced warming above 15C during transport, partial hydration occurs, increasing aggregate formation upon reconstitution even if you follow correct technique

However, when the low hydrophobicity region was replaced with the hydrocarbon staple moiety, the hydrophobic area was integrated and became bigger and more hydrophobic, leading to a significant increase in hemolytic activity (Figure 3C)

Kwai, N

Deviating from these guidelines without direct medical supervision can compromise the safety and effectiveness of the treatment and may even void manufacturer support