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Additionally, PXR activation leads to the upregulation of SREBP2 and HMGCR and broadly induces cholesterol synthesis both in mice experiments and clinical researches (85)

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XETRA-DAX: UR9) is a global specialty pharmaceutical group focused on developing and commercialising treatments for patients with genetic, metabolic, systemic, and life-threatening, acute disorders, as well as healthcare solutions for the general population