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Tirzepatide is a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist licensed in the UK for the treatment of type 2 diabetes mellitus and, more recently, for chronic weight management in adults with obesity or overweight with weight-related comorbidities

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suggest that GH impacts adipose tissue in a depot-specific manner and impacts other features of adipose tissue (for example, senescence, adipocyte subpopulations, and fibrosis), all of which [may] impact lipolysis

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