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Description

Cancer Cell 17 , 225234 (2010)

Gnecchi MZ, Zhang A, Ni VJ, Dzau

Early research on ferroptosis-characteristic cell death is dated back to the 1950s and 1960s, led by Harry Eagle who demonstrated that cysteine depletion reduced glutathione and led to cell death, whereas cysteine synthesis protected cell death by restoring glutathione [94,95,96]