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You can still take them alone, but together they give the best results and keep your cells healthy for the long term

South Asian phenotype : the metabolic risk lands a step earlier (more visceral fat and earlier dysglycemia at a given BMI), so the target can run a notch higher

Many trials included dietary advice, a calorie deficit, or structured exercise

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Treatment must be provided by specialist weight management services, is limited to a maximum of 2 years, and requires specific weight loss targets to continue