It will be released early next year
As the newest addition to incretin-based drugs, tirzepatide harbors the potential to counteract most of the pathogenetic mechanisms underpinning CKD in T2D displaying unprecedented features in terms of glucose and weight lowering, accompanied by promotion of insulin sensitivity, control of SBP, dyslipidemia, and biomarkers of inflammation and endothelial dysfunction
25 , 26 Inflammation mediated by oxidative stress increases the rate of hyaluronan degradation, thereby contributing to the development of several joint disorders, namely, osteoarthritis
Additionally, researchers found that extract from walnuts, whose polyphenols are the most effective among all nuts, has a remarkable ability to shield PC12 cells from oxidative stress caused by amyloid beta peptide (594)
doi: 10.3389/fendo.2022.869414