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Numerous recent evidence [80,88,89,90] have shown that low doses of dietary nutrients promote neuroprotection via the activation of the Nrf2 pathway in order to prevent or attenuate OS and cognitive damage in vitro and in vivo

The macronutrient composition of the control LieberDeCarli diet from Dyets, Inc., in percentage of total calories is 47% carbohydrate, 35% fat, and 18% protein, whereas the EtOH liquid diet is 35% fat, 18% protein, 19% carbohydrate, and 28% ethanol

PMID 21402995

found that montelukast can effectively reduce oxidative stress and apoptosis in chondrocytes and improve the viability of chondrocytes (Li et al., 2021)

A: Safety data in humans is limited