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Overall, this work proposed a convenient, safe, and effective rectal drug delivery strategy, providing a new candidate for the prevention and treatment of radiation-induced proctitis, and also providing a reference for the design of multifunctional local delivery systems in radiation-associated tissue injury

539 Glutamate transporter currents, which are a direct measure of the glutamate transport, decrease to ~15% of their level in young adult astrocytes

As defined in the clinical practice guidelines established by Kidney Disease: Improving Global Outcomes (KDIGO), the diagnostic threshold for anemia in CKD is a hemoglobin (Hb) level below 13.0 g/dL for male patients and under 12.0 g/dL for females who are not pregnant (KDIGO, 2024)