A substance whose presence is essential for the activity of an enzyme
Since the standard one-electron reduction potential of (-TO /-TOH) couple is about 500 mV and (Asc /AscH ) couple is 280 mV, vitamin C can regenerate vitamin E (-TOH) from its radical form (-TO ) according to the reaction Glutathione Tripeptide Glutathione (GSH) is a major multifunctional cellular thiol antioxidant and redox buffer
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Since HEDS contains no glutathione moiety, alterations at the scaffold site could provide further insights regarding GSSEtOH as a potential reaction intermediate
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