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A: Unregulated

716,717 Interestingly, MRI confirmed higher iron levels in stroke patients, and iron levels in the brain were associated with the severity of cerebral infarction, while iron-dependent lipid peroxidation, or ferroptosis, occurred in neurons in the infarct area during ischemic stroke

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464,465 Furthermore, liposome-encapsulated trans-crocetin (TC) is longer lasting than free TC, with a longer duration of oxygenation in vitro and an extended half-life in vivo in the context of CARDS