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He later said he "would never have conceived that there was any potential therapeutic benefit" [3]

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These results demonstrated that tirzepatide 10 and 15 mg had the lowest NNT, where an additional patient achieving the 5% weight reduction threshold would be observed if treating an additional 1.47 and 1.46 patients with tirzepatide 10 and 15 mg, respectively, rather than placebo

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