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Name: how semaglutide weight loss mechanism of for management of obesity, NASH, and Semaglutide ameliorates osteoarthritis progression through
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The estimated annual cost of obesity in Canadaincluding hospitalizations, medications, long-term care, and premature mortalityis approximately $27 billion per year

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GLP-1RAs may counteract growth-promoting milieu through improved insulin sensitivity and reduced circulating insulin levels, which is particularly relevant in obesity- and diabetes-associated cancers, such as breast cancer, CRC and EC (75,80,81,176)