10.1111/j.1365-2036.2010.04522.x 85
[3] [4] Because retatrutide is unlicensed, it may only be supplied to a patient in the UK on a named-patient basis a route known as an unlicensed 'Special' where a registered prescriber takes personal responsibility for its use, confirms that no suitable licensed alternative exists, and ensures the patient is fully informed of its unlicensed status
Becker K, Tilley L, Vennerstrom JL, Roberts D, Rogerson S, et al
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It's often used for medications which affect nerve or hormonal pathways, like metformin for type 2 diabetes and diuretics for high blood pressure