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PPIs, including omeprazole (Prilosec) and pantoprazole (Protonix), rank among the most widely dispensed drug classes in the United States, with an estimated 15.5 million Americans using a PPI chronically as of 2023 [2]

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The medication is still under patent protection by its manufacturer, Novo Nordisk, which means other companies cant legally produce a generic equivalent yet

Strains such as Lactobacillus rhamnosus GG, Bifidobacterium lactis BB-12, and Saccharomyces boulardii have some evidence for managing general digestive symptoms, though no strain is specifically proven for Ozempic-related side effects

Appetite support GLP-1 pathways can help eligible patients reduce appetite and food noise