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Lastly, research has shown that utilizing an M2-targeting peptide-modified liposome carrier for YY1-targeted therapy in M2 macrophages is highly effective in inhibiting PCa cell lung metastasis and exhibits synergistic antitumor effects when combined with PD-1 blockade (Tsang et al., 2020)

Needle electrodes were placed at the vertex (active) and immediately below the pinna of the test ear (reference) and contralateral ear (ground)

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[1] For those on oral therapy, a repeat B12 level may be checked after several months to confirm response