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Patients with higher white matter hyperintensities have significantly higher BBB leakage as evaluated by DCE-MRI (227)

Eur J Clin Nutr (2005) 59:72730.10.1038/sj.ejcn.1602133 53 VisioliFCarusoDGrandeSBosisioRVillaMGalliGet alVirgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients

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12,21,22 The opening of the mitochondrial permeability transition pore under pathological conditions, such as oxidative stress, calcium overload, or energy depletion, leads to disruption of the mitochondrial membrane potential and the release of proapoptotic factors, ultimately culminating in cell death