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In preclinical models, female mice showed greater increases in muscle mass in response to MSTN blockade, whereas male mice demonstrated more prominent reductions in fat mass.[58] However, clinical evidence for sex-based differences in patient outcomes remains limited, partly because most clinical studies have focused on assessing the safety of the drug in postmenopausal women or have primarily targeted elderly individuals with sarcopenia

Yes, Zepbound is classified as a peptide medication

However, a majority of the patients reach adulthood without any other symptoms than decreased stamina and fatigue 20,21

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