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The results of a recent study indicate that pitavastatin (available already in Poland), the metabolism of which practically does not involve cytochrome P450 isoenzymes (a few percent involvement of CYP 2C8 and 2C9), is more likely than pravastatin to contribute to a decrease in immune activation and arterial inflammation in HIV-infected individuals [389]

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The current evidence is based on its known biological mechanisms and promising results from animal studies on nerve injury, inflammation, and tissue repair