Results Cystine deprivation leads to rapid death of TNBC cells by mitochondrial oxidative stress independent of GSH loss To investigate the dependence of BC cells on Cyss, we first examined the cytoplasmic Cys/Cyss content in TNBC (Hs 578T and MDA-MB-231) and non-TNBC cell lines (MCF7), cultured for 8 h in the absence of Cyss or in the presence of buthionine sulfoximine (BSO), an inhibitor of GCL (Fig
Kojic Acid (5,000mg): Reduces pigmentation and dark spots
As a tropane-derived compound, Tesofensine represents a research subject in the broader field of small molecule structure-activity research
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