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This article presents a four-phase approach to selecting, counselling and following up patients to help GPs in prescribing GLP-1RAs safely and effectively (see Box 1)

a form of diabetes which typically develops in later life and is associated with being obese

doi:doi:10.1161/JAHA.125.043373

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The most common side effects of compounded semaglutide and compounded tirzepatide are similar to their brand-name counterparts and are typically gastrointestinal in nature, including: Nausea Vomiting Diarrhea Constipation Bloating or gas Decreased appetite or early satiety These side effects are usually mild to moderate and tend to improve over time, especially with gradual dose escalation under provider supervision