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Biological replicates are shown as individual data points, with a bar graph representing the mean and error bars showing SD

The breakdown of protein homeostasis (misfolding, mislocalization, and aggregation of proteins) is a core characteristic of aging

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Wegovy results in greater weight loss than Saxenda, as demonstrated in a network meta-analysis that demonstrated a more than 5% total weight loss more often in the Wegovy recipientsan average weight loss of 15.8 kg in the Wegovy arm versus 6.4 kg in the Saxenda arm, in a representative trial from the meta-analysis at 68 weeks