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A benchmark, expand, and calibration (BenchExCal) trial emulation approach for using real-world evidence to support indication expansions: design and process for a planned empirical evaluation

Combining phentermine and tirzepatide amplifies sympathomimetic stress on the cardiovascular system, raising risks of arrhythmia and hypertensive crisis

The enhanced lipolysis pulls fatty acids from stubborn areas like the midsection that typically resist standard dieting approaches

Still, doctors should be on the lookout for this possible complication in GLP-1 users, the authors say

Widely consumed as chimarro , yerba mate is a staple in southern states like Rio Grande do Sul