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If we add poor sleep quality to the equation, we have a combination of many factors

An emerging hypothesis of insular dysfunction

Abstract Alzheimers disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory impairment, and hallmark neuropathological features, including extracellular amyloid- (A) plaques and intracellular neurofibrillary tangles formed by hyperphosphorylated tau

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Of note, the NAC/LA/Br mixture was totally ineffective in UtMECs (Figure 5(d))