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Introduction Many individuals find themselves on a persistent quest for effective weight management, often encountering plateaus despite dedicated efforts in diet and exercise

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No large-scale studies have evaluated microdosing specifically

Obesity promotes an immunosuppressive tumor microenvironment that profoundly impairs the ability of CD8+ TILs to effectively respond to and kill cancer cells 68

Some frequently used dopamine receptor antagonists, such as metoclopramide, domperidone and risperidone, elevates both serum and central (cerebrospinal fluid) PRL levels and by doing so do not disturb energy and glucose metabolism, while other dopamine antagonists, such as olanzapine, induce impaired glucose tolerance and obesity since they do not increase central prolactin levels (78)