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This is important because shifts in fat distribution and in body composition that occur during the menopausal transition are associated with increased cardiometabolic risk factors, including elevated blood pressure, elevated low-density lipoprotein, and obesity

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This is mechanistically demonstrated in breast cancer models, where SFN, by activating the Nrf2 pathway, reduces the secretion of prostaglandin E2 (PGE2) from tumor cells, thereby triggering MDSCs to switch from an immunosuppressive to an immunogenic phenotype and inhibiting their expansion (76)

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28843): promoting intestinal digestion, absorption, and structural integrity in juvenile grass carp ( Ctenopharyngodon idella )