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In the CY 2025 PFS final rule (89 FR 98228 through 98275), we codified regulations implementing section 11101 of the IRA in newly added 42 CFR part 427, chapter IV, including new provisions at 427.200 and 427.201 to codify the policies regarding the computation of the inflation-adjusted beneficiary coinsurance, defined in 427.200, for Part B rebatable drugs as required by section 1847A(i)(5) of the Act

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Core Benefits and Mechanisms of BPC-157 Current research points to several potential therapeutic mechanisms for BPC-157, although human clinical data remains limited