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Proceedings (Baylor University Medical Center) 2025 Pooled analysis of 3 RCTs covering 878 patients, mean weight reduction 14.33% across doses, dose-response confirmed
Behavioral changesconsistent physical activity, protein-rich meals, and sleep qualityremain foundational
doi: 10.1056/NEJMe2312646 266 LewingtonSClarkeRQizilbashNPetoRCollinsRCollaborationPS
By the two to three month mark it describes remaining levels as negligible and effectively cleared
In sensitivity analysis, we also included an isoform of l-carnitine, acetyl-carnitine, proxied by three genetic variants reaching genome-wide significance from the same GWAS as l-carnitine [20]
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