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Key highlights include a systematic delineation of both core and emerging ferroptosis-regulatory networks, a detailed analysis of the pathological contributions of ferroptosis across distinct CVDs, and a critical evaluation of evolving therapeutic strategies ranging from small-molecule inhibitors to advanced nanomedicine-based approaches

Several studies have also demonstrated that, unlike TRE which decreases lean mass, treatment with tirzepatide, liraglutide or semaglutide reduces body weight with small effects on lean mass (61, 64, 65)

Clinical studies show that patients using semaglutide can achieve an average weight reduction of up to 15% of their body weight over 68 weeks

Human data are limited and primarily from aging studies rather than fertility outcomes

But theyll go much further