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Week 8 Labs (End of Cycle) Full repeat of baseline panel Serum copper and ceruloplasmin PSA (men) Post-Washout (Week 12) IGF-1 to confirm return toward baseline Fasting glucose The Endocrine Society's 2011 Clinical Practice Guideline on adult growth hormone deficiency provides reference ranges and monitoring intervals for IGF-1 that are directly applicable to secretagogue-based protocols, even though the guideline addresses GH replacement rather than secretagogue use

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Excess copper can promote ferritin depletion and disrupt iron metabolism, thereby sensitizing cardiomyocytes to ferroptosis, a process that synergistically aggravates I/R injury [67]

Use bacteriostatic water (BAC) Contains 0.9% benzyl alcohol for preservation in research solutions