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This may be due to its ability to intercept and neutralize toxins in the GI tract before they are absorbed

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The final structures were deposited in the Protein Data Bank under accession codes 9HMC (PDE 5e ) and 9HMD (PDE 6a ), with detailed data collection and refinement statistics provided in Supplementary InformationSupplementary Table 5

In particular, determining when it makes sense to treat gastroesophageal reflux or perform a reflux repair plays a key role in guideline-based care for affected patients

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