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CYMBALTA showed improvement over placebo on the primary endpoint [change from baseline to end-of-treatment on the Brief Pain Inventory (BPI) Modified Short Form: Adolescent Version 24-hour average pain severity rating] with a p-value of 0.052 from the pre-specified primary analysis, and p-values ranging from 0.011-0.020 from sensitivity analyses which assigned baseline values to missing assessments of some patients who did not complete the trial for various reasons

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