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As crucial regulators of local immune responses and tissue repair, macrophages in diabetic wounds show dysregulated switching from M1 to M2, resulting in a poor regenerative environment, exacerbated tissue damage, and delayed wound healing 63

Targeting cellular senescence with senotherapeutics: senolytics and senomorphics

The single dose, short (1 h) observation period, and lack of placebo arm are limitations in this proof-of-concept study and provide direction for follow-up studies

These unstable molecules target healthy cellslike eggs and spermand cause structural damage

The second component is a copper ion that binds to this peptide chain