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Mechanistically, they activate Nrf2 and block ubiquitin-mediated GPX4 degradation, thereby inhibiting ferroptosis and alleviating cartilage erosion, pain, and gait abnormalities in DMM-induced OA (192)

The combination of BPC-157 and GHK-Cu appears to have synergistic effects, leading to more efficient and effective tissue repair

Beyond skin and hair, the regenerative potential of GHK-Cu is explored in other contexts

Additional preclinical themes include angiogenesis (through endothelial cell migration and tube formation), modulation of inflammatory signalling, and reported effects on cardiac, dermal and neural tissue in animal models