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Furthermore, our patients often respond positively to 600 mg/day of N-acetylcysteine (NAC), which can decrease elevated levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) enzymes by reducing oxidative stress (Sukumaran et al., 2023)

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(PubMed) Holick MF, Matsuoka LY, Wortsman J

If your goal is joint pain from carrying extra weight, the GLP-1 alone is doing real work