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10.1038/s41467-021-21984-w 92 TokumitsuH.SakagamiH

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Clinical Impact: Clinical studies and patient observations have shown that GLP-1 agonists can lead to substantial weight loss in individuals with severe obesity, including those with genetic syndromes like BBS

"Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron"