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doi: 10.1093/hmg/ddab312 40
doi:10.1007/s00345-025-05692-4
Dehydration adds to the tired feeling and often gets missed because thirst cues drop alongside hunger cues
Conversely, TMAO dose-dependently augmented ERK1/2 pathway activation and myofibroblast trans-differentiation, when co-administered with TGF-1 in comparison to TGF-1 or TMAO alone, without affecting SMAD3 phosphorylation (Fig
The lactylated MRE11 is more likely to bind to DNA, thereby promoting the phosphorylation of ATM, and ultimately facilitating the cutting and homologous recombination (HR) at the ends of DNA, mediating the chemoresistance of tumor cells
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