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An emerging mechanism of ferroptosis-like cell death points to cysteine loss as a key trigger, with one study demonstrating that erastin-induced cysteine deprivation triggered an alternative ferroptosis-like death pathway distinct from GPX4 inhibition, and that cysteine levels themselvesnot just glutathione levelswere the primary determinant of cellular fate

Daytime (6:0024:00 h) and nighttime (24:006:00 h) outcomes were also assessed

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