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In 2022, catalpol was classified as Class 1.2 clinical by China Suzhou Yusen New Drug Development Co., Ltd., and is now recognized for its potential to improve cerebral ischemia injury
For example, the genes encoding transferrin receptor (TFRC), glucose transporters and the master antioxidant regulator NRF2 are closely associated with the pathological progression of AD (49)
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Subsequently, the homogenized mixture was centrifuged at 492 g for 10 min
In recent years, necroptosis, a novel subtype of regulated necrosis, and autophagy, a form of homeostatic housekeeping mechanism have witnessed a burgeoning interest owing to their potential to regulate and alleviate CP-induced AKI
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