And the foundational paper was retracted
The closest thing to an evidence-based loose skin protocol is: adequate protein, resistance training, gradual weight loss when possible, sun protection, retinoids for facial use, topical GHK-Cu as adjunct, hydration, and patience
3 Additionally, another study analyzing the effects of exercise-induced stress (due to chronic swimming) on plasma T levels in male rats demonstrated the known negative correlation between stressors and testosterone ( chronic swimming stress test induced a twofold decrease in plasma testosterone levels )
Therefore, this section focuses on exploring the beneficial effects of protein intake
Based on the whole-body turnover rate of 1.33%/day for carnosine and the total amount of carnosine (45.5 g) in a 70-kg man (Spelnikov and Harris 2019), it can be estimated that the physiological need for this dipeptide by a 70-kg subject is 606 mg/day