The article lists the clinical goal as its own dosing consideration, noting that the objective may be weight loss, glucose control, appetite suppression, or cardiovascular benefit, and that each informs the strategy differently
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Its anti-inflammatory effects are mediated through the downregulation of pro-inflammatory cytokines, including IL-1, IL-6, and TNF-, thereby attenuating inflammation-induced tissue damage [20]
Our results demonstrate that carnitine establishes a stable interaction with COX-2 and inhibits it at a moderate level, supporting the notion that carnitine could be further explored as a natural molecule with therapeutic potential against inflammation and tumor development
Role of the Funder/Sponsor : The funders had no role in the design and conduct of the study